Description
Dermorphin is a naturally occurring opioid peptide originally isolated from the skin of South American tree frogs (Phyllomedusa sauvagei). It is known for its extremely potent activity at mu-opioid receptors, showing a significantly higher binding affinity compared to morphine. Dermorphin 5mg is provided strictly for laboratory and scientific research purposes, offering researchers a valuable tool for studying opioid receptor function, pain modulation pathways, and potential therapeutic applications of peptide-based analgesics.
Key Features
-
Peptide: Dermorphin
-
Quantity: 5mg (lyophilized powder)
-
Purity: ≥ 98% (HPLC tested)
-
Form: Lyophilized powder for reconstitution
-
Research Use: Mu-opioid receptor studies, neuropharmacology, peptide-receptor interactions
Scientific Background
Dermorphin has attracted attention due to its unique structure and unusually high potency. Compared to traditional opioid compounds, it binds selectively and strongly to mu-opioid receptors, producing pronounced analgesic effects in animal studies at doses far lower than morphine. This makes it an important subject for research into novel pain management strategies and opioid receptor pharmacodynamics. Additionally, its peptide-based structure provides insights into the role of amino acid sequences in receptor activation and signaling.
Applications in Research
-
Investigating mu-opioid receptor selectivity and binding affinity
-
Studying peptide-based analgesics and alternatives to traditional opioids
-
Exploring pain modulation pathways in neuropharmacological models
-
Comparative studies on the efficacy and potency of natural versus synthetic opioids
Storage Guidelines
-
Store at -20°C in a dry, dark environment
-
Avoid repeated freeze-thaw cycles
-
Once reconstituted, store in sterile solvent at 2–8°C and use within short duration
